Screening of voluntary blood donors by HCV related antibody test kit (Imucheck).
نویسندگان
چکیده
منابع مشابه
Management of blood donors whose donations are repeatedly falsely positive by the HIV antibody screening test.
Since 1985, over 1,800,000 donations have been screened by the West Midlands Regional Blood Transfusion Service for antibody to HIV. Twelve regular donors gave three or more donations that were alternatingly positive and negative in the screening test, but not confirmed to be HIV positive by supplementary testing. Extensive investigation of six of these donors, including the polymerase chain re...
متن کاملPresence of lower temperature-dependent antibody with low avidity to C100-3 (HCV) antigen in voluntary blood donors.
Serum samples with lower temperature-dependent antibody with low avidity to C100-3 (HCV) antigen were found in 0.19% of 23,197 voluntary blood donors at this blood center. They showed positive C100-3 antibody activity at 24 C but not at 37 C. The antibody activity bound to C100-3 antigen at lower temperature disappeared after incubation for 60 min at 37 C or treatment with 8 M urea. Other marke...
متن کاملDetection of hepatitis C virus (HCV) core-specific antibody suggests occult HCV infection among blood donors.
BACKGROUND Blood transfusion safety is based on reliable donor screening for transmissible infections such as the hepatitis C virus (HCV) infection. STUDY DESIGN AND METHODS A novel HCV core-specific antibody was assayed on random single donations from 2007 first-time blood donors who tested negative for anti-HCV and HCV RNA on routine screening. Sample collection broke the code between donat...
متن کاملUpdate on HCV genotypes among Iranian blood donors
Abstract Background and Objectives Hepatitis C (HCV) infection is one of the main causes of chronic hepatitis diseases all over the world. HCV is a transfusion transmitted virus and a serious threat to general health. HCV genotyping has an important role in tracing routes of infection. This study aimed at investigating the changes in distribution pattern of HCV genotypes among Iranian blood d...
متن کاملLow Specificity of the Third Generation Elisa for Hcv Detection in Voluntary Blood Donors in India
Objective Third generation anti-HCV ELISA is currently recommended for the diagnosis of HCV infection. We determined its specificity in voluntary blood donors (VBDs) and patients with chronic liver disease (CLD) in relation to confirmatory line immunoassay (LIA) and reverse transcription polymerase chain reaction (RT-PCR). Material and Methods: 1926 serum samples of VBDs and 16 HCV related CLD ...
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ژورنال
عنوان ژورنال: Journal of the Japan Society of Blood Transfusion
سال: 1993
ISSN: 1883-8383,0546-1448
DOI: 10.3925/jjtc1958.39.726